Botox works to lessen and smooth the appearance of wrinkles and fine lines in certain areas of the face. When Botox is injected into a muscle near a wrinkle, neuromuscular blockers limit muscle contractions in the area of the injection. This permits muscles to relax and the skin to smooth out and reduce unwanted wrinkles. Botox works in areas that are wrinkled due to excessive squinting and frowning like the forehead, corners of the eyes and above the nose. Botox relaxes these muscles so the skin is not continually pulled which gives the skin time to smooth out. Botox also helps loosen tight muscles in the neck and relieve headaches caused by tension or muscle spasms.